USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9NR45 USC-OGP 2-DE database:  Q9NR45 Q9NR45 General information about the entry View entry in simple text format Entry name SIAS_HUMAN Primary accession number Q9NR45 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Sialic acid synthase; AltName: Full=N-acetylneuraminate synthase; EC=2.5.1.56; AltName: Full=N-acetylneuraminate-9-phosphate synthase; EC=2.5.1.57; AltName: Full=N-acetylneuraminic acid phosphate synthase; AltName: Full=N-acetylneuraminic acid synthase;. Gene name Name=NANS Synonyms=SAS Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1196: pI=6.47; Mw=40351 SPOT OGP-1204: pI=6.86; Mw=39011 Cross-references UniProtKB/Swiss-Prot Q9NR45; SIAS_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SIAS_HUMAN Primary accession number Q9NR45 Secondary accession number(s) B2RE98 Q8WUV9 Q9BWS6 Q9NVD4 Sequence was last modified on  May 15, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 154) Name and origin of the protein Description RecName: Full=Sialic acid synthase; AltName: Full=N-acetylneuraminate synthase; EC=2.5.1.56; AltName: Full=N-acetylneuraminate-9-phosphate synthase; EC=2.5.1.57; AltName: Full=N-acetylneuraminic acid phosphate synthase; AltName: Full=N-acetylneuraminic acid synthase; Gene name Name=NANS Synonyms=SAS Encoded on Name=NANS; Synonyms=SAS Keywords 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Disease mutation; Dwarfism; Mental retardation; Polymorphism; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF257466; AAF75261.1; -; mRNA EMBL AK001659; BAA91818.1; -; mRNA EMBL AK316608; BAG38195.1; -; mRNA EMBL AL137073; CAI13886.1; -; Genomic_DNA EMBL CH471105; EAW58867.1; -; Genomic_DNA EMBL BC000008; AAH00008.1; -; mRNA EMBL BC019315; AAH19315.1; -; mRNA CCDS CCDS6733.1; -; . RefSeq NP_061819.2; NM_018946.3; . UniGene Hs.522310; -; . UniGene Hs.665191; -; . PDB 1WVO; NMR; -; A=294-359 PDBsum 1WVO; -; . ProteinModelPortal Q9NR45; -; . SMR Q9NR45; -; . BioGrid 119921; 37; . IntAct Q9NR45; 19; . MINT MINT-5002014; -; . STRING 9606.ENSP00000210444; -; . iPTMnet Q9NR45; -; . PhosphoSitePlus Q9NR45; -; . SwissPalm Q9NR45; -; . BioMuta NANS; -; . DMDM 20978759; -; . REPRODUCTION-2DPAGE IPI00147874; -; . EPD Q9NR45; -; . MaxQB Q9NR45; -; . PaxDb Q9NR45; -; . PeptideAtlas Q9NR45; -; . PRIDE Q9NR45; -; . DNASU 54187; -; . Ensembl ENST00000210444; ENSP00000210444; ENSG00000095380; . GeneID 54187; -; . KEGG hsa:54187; -; . UCSC uc004ayc.4; human; . CTD 54187; -; . DisGeNET 54187; -; . GeneCards NANS; -; . HGNC HGNC:19237; NANS; . HPA HPA019223; -; . MalaCards NANS; -; . MIM 605202; gene; . MIM 610442; phenotype; . neXtProt NX_Q9NR45; -; . OpenTargets ENSG00000095380; -; . PharmGKB PA134978885; -; . eggNOG ENOG410IHMI; Eukaryota; . eggNOG COG2089; LUCA; . GeneTree ENSGT00390000011081; -; . HOGENOM HOG000284783; -; . HOVERGEN HBG000665; -; . InParanoid Q9NR45; -; . KO K05304; -; . OMA AYPSKIE; -; . OrthoDB EOG091G0D9G; -; . PhylomeDB Q9NR45; -; . TreeFam TF324826; -; . BioCyc MetaCyc:HS01818-MONOMER; -; . BRENDA 2.5.1.57; 2681; . Reactome R-HSA-4085001; Sialic acid metabolism; . ChiTaRS NANS; human; . EvolutionaryTrace Q9NR45; -; . GeneWiki NANS; -; . GenomeRNAi 54187; -; . PRO PR:Q9NR45; -; . Proteomes UP000005640; Chromosome 9; . Bgee ENSG00000095380; -; . CleanEx HS_NANS; -; . ExpressionAtlas Q9NR45; baseline and differential; . Genevisible Q9NR45; HS; . GO GO:0005737; C:cytoplasm; NAS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0050462; F:N-acetylneuraminate synthase activity; IEA:UniProtKB-EC; . GO GO:0008781; F:N-acylneuraminate cytidylyltransferase activity; NAS:UniProtKB; . GO GO:0047444; F:N-acylneuraminate-9-phosphate synthase activity; TAS:Reactome; . GO GO:0009103; P:lipopolysaccharide biosynthetic process; NAS:UniProtKB; . Gene3D 3.20.20.70; -; 1; . Gene3D 3.90.1210.10; -; 1; . InterPro IPR006190; AFP_Neu5c_C; . InterPro IPR013785; Aldolase_TIM; . InterPro IPR006013; Antifreeze_III; . InterPro IPR013132; Neu5Ac_N; . InterPro IPR013974; SAF; . Pfam PF03102; NeuB; 1; . PRINTS PR00357; ANTIFREEZIII; . SMART SM00858; SAF; 1; . SUPFAM SSF51269; SSF51269; 1; . PROSITE PS50844; AFP_LIKE; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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